MS Services offered include the following:

  • EI-MS : low resolution, nominal mass accuracy; high resolution, with internal reference (typically PFK), 5 ppm accuracy; or small volatile organic compounds (<1000 Da); performed on Waters Autospec sector, with sample introduced through direct probe insertion.
  • GC-MS/MS: low resolution, nominal mass accuracy, performed on QMGC
  • GC-MS: low resolution, nominal mass accuracy; high resolution, with internal reference (typically PFK), 5 ppm accuracy; for small volatile organic compounds (<1000 Da), performed on Waters Autospec sector GCMS
  • MALDI-MS: linear TOF, low resolution, <150 ppm external clibration, <100 ppm for internal calibration; reflector TOF, high resolution, <25 ppm external calibration, <5 ppm internal calibration; wide applications including biomolecules, polymers, aromatic compound, and inorganic material, performed on Bruker Ultraflex
  • ESI, APCI, nanoESI-MS: low resolution, mass error within 0.2 Da; for small molecules (>50 Da) or macromolecules (m/z of the multiply charged ions <3000 Da); wide applications including biomolecules, organics, and polymers, performed on Bruker HCTultra.
  • ESI high resolution: Mass error within 5 ppm, performed on Waters QTof
  • LC-MS/MS: low resolution, either CID or ETD ion activation, mass error within 0.2 Da; house capillary LC column: Agilent ZORBAX SB-C18, 150 × 0.5 mm, 5 µm; mostly used for peptides and small molecules, performed on Bruker HCTultra.
  • UPLC-MS/MS: high resolution, high sensitivity, higher chance of contamination, performed on Waters QToF


Internal UA Users: EI-MS, GC-MS, and GC-MS/MS are free of charge. Regardless of sample submission or user running the samples, ESI, APCI, nanoESI low resolution, ESI high resolution, LC-MS/MS, and UPLC-MS/MS  are charged at $8 per instrument hour, and MALDI-MS is charged at $5 per hour.

External Users: Generally $100 per hour for samples submitted for MS service. For EIHR MS, $40 per sample for external academic users. Other prices can be negotiated.

Sample Submission Forms:

Samples suitable for EI ionization (on GCMS instruments) are generally volatile and thermally stable small organic molecules (typically under 800Da, high mass up to1200 Da).  Ionic, nonvolatile,  or large molecules are suitable for ESI (on QTof and LCMS instruments) or MALDI ionization.

MALDI-submital Form      QMGC/MS-submittal Form      QTof-submittal Form

LCMS-submittal Form        GCMS-submittal Form         EI-submittal Form


Instrument user trainings are offered on all mass spectrometers to frequent users including faculty, staff, and students. Please contact the Facility Manager, Dr. Qiaoli Liang (, 2053482627) to arrange training.